Iris Publishers Journal of Dentistry & Oral Health

  Authored by  Iquebal Hasan, Focal acantholytic dyskeratosis (FAD), also previously referred to as warty dyskeratoma or isolated Darier’s disease, is a condition characterized by cutaneous lesions, which can rarely present in the oral cavity. “In 1972, Akerman established different subtypes of FAD: 1) Clinically nonsuggestive solitary lesions that showed histopathological areas of FAD, 2) Popular lesions with multiple histopathological areas of FAD, 3) Nodular lesions with only one histopathological area of FAD (warty dyskeratoma) and 4) Systemic disorders with multiple lesions similar to Darier disease [1]. Fewer than 50 cases of focal acantholytic dyskeratosis have been reported in the oral cavity. The reported lesion usually appeared as asymptomatic, solitary, white nodules, papules, or patches on bonebound mucosa, sometimes with a ‘rough surface’ and a depressed center. Males were affected slightly more than females, and the lesions were most common in the fifth to sevent...